6R37
T. brucei FPPS in complex with 2-(5-chlorobenzo[b]thiophen-3-yl)acetic acid
Summary for 6R37
| Entry DOI | 10.2210/pdb6r37/pdb |
| Descriptor | Farnesyl pyrophosphate synthase, (5-chloro-1-benzothiophen-3-yl)acetic acid, DIMETHYL SULFOXIDE (3 entities in total) |
| Functional Keywords | sterol biosynthesis, farnesyl diphosphate synthase, trypanosoma brucei, homodimer, transferase |
| Biological source | Trypanosoma brucei |
| Total number of polymer chains | 1 |
| Total formula weight | 42474.02 |
| Authors | Muenzker, L.,Petrick, J.K.,Schleberger, C.,Jahnke, W. (deposition date: 2019-03-19, release date: 2020-04-08, Last modification date: 2024-01-24) |
| Primary citation | Muenzker, L. Targeting Trypanosoma brucei FPPS by Fragment-based drug discovery Thesis, 2019 Cited by DOI: 10.17192/z2019.0500PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report
