Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

6R37

T. brucei FPPS in complex with 2-(5-chlorobenzo[b]thiophen-3-yl)acetic acid

Functional Information from GO Data
ChainGOidnamespacecontents
A0004161molecular_functiondimethylallyltranstransferase activity
A0004337molecular_function(2E,6E)-farnesyl diphosphate synthase activity
A0004659molecular_functionprenyltransferase activity
A0005737cellular_componentcytoplasm
A0008299biological_processisoprenoid biosynthetic process
A0016740molecular_functiontransferase activity
A0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
A0045337biological_processfarnesyl diphosphate biosynthetic process
A0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues6
Detailsbinding site for residue 3N2 A 401
ChainResidue
AASN49
AARG50
ATHR217
APHE251
ALYS361
ATHR362

site_idAC2
Number of Residues6
Detailsbinding site for residue DMS A 402
ChainResidue
AGLN252
AASP256
ACYS279
AASP175
ATYR205
ALYS212

Functional Information from PROSITE/UniProt
site_idPS00444
Number of Residues13
DetailsPOLYPRENYL_SYNTHASE_2 Polyprenyl synthases signature 2. MGeyFQVqDDVmD
ChainResidueDetails
AMET247-ASP259

site_idPS00723
Number of Residues15
DetailsPOLYPRENYL_SYNTHASE_1 Polyprenyl synthases signature 1. LVeDDim..DnsvtRRG
ChainResidueDetails
ALEU100-GLY114

238895

PDB entries from 2025-07-16

PDB statisticsPDBj update infoContact PDBjnumon