6R05

T. CRUZI FPPS IN COMPLEX WITH N-BENZYL-6-METHYLPYRIDIN-2-AMINE

Summary for 6R05

• Entry DOI: 10.2210/pdb6r05/pdb
• Descriptor: Farnesyl diphosphate synthase, 6-methyl-~{N}-(phenylmethyl)pyridin-2-amine, SULFATE ION, ... (7 entities in total)
• Functional Keywords: farnesyl diphosphate synthase, sterol biosynthesis, farnesyl pyrophosphate, homodimer, transferase
• Biological source: Trypanosoma cruzi
• Total number of polymer chains: 1
• Total formula weight: 41980.94

Authors

Petrick, J.K.,Muenzker, L.,Schleberger, C.,Jahnke, W. (deposition date: 2019-03-12, release date: 2020-04-01, Last modification date: 2024-02-07)

• Primary citation: Petrick, J.K.,Jahnke, W.; Targeting farnesyl pyrophosphate synthase of Trypanosoma cruzi by fragment-based lead discovery; Thesis, 2019; DOI: 10.17192/z2019.0501

Experimental method

X-RAY DIFFRACTION (1.57 Å)