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6R05

T. CRUZI FPPS IN COMPLEX WITH N-BENZYL-6-METHYLPYRIDIN-2-AMINE

Functional Information from GO Data
ChainGOidnamespacecontents
A0004659molecular_functionprenyltransferase activity
A0008299biological_processisoprenoid biosynthetic process
A0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue JNE A 501
ChainResidue
APRO111
AARG115
APHE116
AGLU183

site_idAC2
Number of Residues11
Detailsbinding site for residue SO4 A 502
ChainResidue
AGLN91
AARG108
AHOH637
AHOH664
AHOH684
AHOH695
AGLY47
ALYS48
ATYR49
APHE50
AARG51

site_idAC3
Number of Residues3
Detailsbinding site for residue DMS A 503
ChainResidue
AASP98
AGLN167
ALYS207

site_idAC4
Number of Residues2
Detailsbinding site for residue ACT A 504
ChainResidue
ATYR11
AASP12

site_idAC5
Number of Residues4
Detailsbinding site for residue ACT A 505
ChainResidue
APHE50
ATYR213
APHE246
ALYS356

site_idAC6
Number of Residues5
Detailsbinding site for residue ZN A 506
ChainResidue
AASP98
AASP102
AHOH610
AHOH612
AHOH649

site_idAC7
Number of Residues6
Detailsbinding site for residue ZN A 507
ChainResidue
AASP250
AHOH607
AHOH626
AHOH634
AHOH768
AHOH777

Functional Information from PROSITE/UniProt
site_idPS00444
Number of Residues13
DetailsPOLYPRENYL_SYNTHASE_2 Polyprenyl synthases signature 2. IGeyFQVqDDVmD
ChainResidueDetails
AILE242-ASP254

site_idPS00723
Number of Residues15
DetailsPOLYPRENYL_SYNTHASE_1 Polyprenyl synthases signature 1. LVeDDim..DgsvmRRG
ChainResidueDetails
ALEU95-GLY109

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PDB entries from 2024-11-20

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