6QYX

p38(alpha) MAP kinase with the activation loop of ERK2

6QYX の概要

• エントリーDOI: 10.2210/pdb6qyx/pdb
• 関連するPDBエントリー: 2NPQ
• 分子名称: Mitogen-activated protein kinase 14,Mitogen-activated protein kinase 1,Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total)
• 機能のキーワード: nled, effector, t3ss, map kinase, phosphorylation, transferase
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 42513.55

構造登録者

Livnah, O.,Eitan-Wexler, M.,Vinograd, N. (登録日: 2019-03-10, 公開日: 2020-04-01, 最終更新日: 2024-05-01)

• 主引用文献: Gur-Arie, L.,Eitan-Wexler, M.,Weinberger, N.,Rosenshine, I.,Livnah, O.; The bacterial metalloprotease NleD selectively cleaves mitogen-activated protein kinases that have high flexibility in their activation loop.; J.Biol.Chem., 295:9409-9420, 2020; PubMed: 32404367; DOI: 10.1074/jbc.RA120.013590

実験手法

X-RAY DIFFRACTION (1.66 Å)