6QPQ
The structure of the cohesin head module elucidates the mechanism of ring opening
Summary for 6QPQ
Entry DOI | 10.2210/pdb6qpq/pdb |
Descriptor | Structural maintenance of chromosomes protein,Structural maintenance of chromosomes protein, Sister chromatid cohesion protein 1 (3 entities in total) |
Functional Keywords | cohesin, cell division, genome regulation, sister chromatid cohesion, smc, kleisin, cell cycle |
Biological source | Chaetomium thermophilum var. thermophilum DSM 1495 More |
Total number of polymer chains | 4 |
Total formula weight | 230471.83 |
Authors | Li, Y.,Muir, K.W.,Panne, D. (deposition date: 2019-02-14, release date: 2020-02-05, Last modification date: 2020-03-18) |
Primary citation | Muir, K.W.,Li, Y.,Weis, F.,Panne, D. The structure of the cohesin ATPase elucidates the mechanism of SMC-kleisin ring opening. Nat.Struct.Mol.Biol., 27:233-239, 2020 Cited by PubMed: 32066964DOI: 10.1038/s41594-020-0379-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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