6QPQ
The structure of the cohesin head module elucidates the mechanism of ring opening
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Structural maintenance of chromosomes protein,Structural maintenance of chromosomes protein | polymer | 453 | 51883.1 | 2 | UniProt (G0SGH3) Pfam (PF02463) | Chaetomium thermophilum var. thermophilum DSM 1495 | |
| 2 | B, D (B, D) | Sister chromatid cohesion protein 1 | polymer | 566 | 63352.9 | 2 | UniProt (Q12158) Pfam (PF04825) Pfam (PF04824) | Saccharomyces cerevisiae S288C | |
| 3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 343 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 242 (UniProt: G0SGH3)
A, C: 1064 - 1264 (UniProt: G0SGH3)
A, C: 1064 - 1264 (UniProt: G0SGH3)
| PDB | External Database | Details |
|---|---|---|
| Ser 243 | - | linker |
| Pro 244 | - | linker |
| Gly 245 | - | linker |
| Leu 246 | - | linker |
| Glu 247 | - | linker |
| Val 248 | - | linker |
| Leu 249 | - | linker |
| Phe 250 | - | linker |
| His 1265 | - | expression tag |
| His 1266 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 230471.8 | |
| All* | Total formula weight | 230471.8 |
