6QIP

Ternary complex of FcRn ectodomain, FcRn binding optimised human serum albumin and the albumin-biniding side chain of the human growth hormone derivative somapacitan

6QIP の概要

• エントリーDOI: 10.2210/pdb6qip/pdb
• 分子名称: Serum albumin, IgG receptor FcRn large subunit p51, Beta-2-microglobulin, ... (8 entities in total)
• 機能のキーワード: complex, albumin binding, long-acting growth hormone, somapacitan, hormone, transport protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 111045.20

構造登録者

Johansson, E. (登録日: 2019-01-21, 公開日: 2020-02-05, 最終更新日: 2024-01-24)

• 主引用文献: Johansson, E.,Nielsen, A.D.,Demuth, H.,Wiberg, C.,Schjodt, C.B.,Huang, T.,Chen, J.,Jensen, S.,Petersen, J.,Thygesen, P.; Identification of Binding Sites on Human Serum Albumin for Somapacitan, a Long-Acting Growth Hormone Derivative.; Biochemistry, 59:1410-1419, 2020; PubMed: 32208682; DOI: 10.1021/acs.biochem.0c00019

実験手法

X-RAY DIFFRACTION (2.45 Å)