6QGP
Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-0769
Summary for 6QGP
Entry DOI | 10.2210/pdb6qgp/pdb |
Descriptor | Phosphodiesterase, ZINC ION, MAGNESIUM ION, ... (9 entities in total) |
Functional Keywords | parasitic phosphodiesterase, hydrolase, african trypanosomiasis, sleeping sickness |
Biological source | Trypanosoma brucei |
Total number of polymer chains | 2 |
Total formula weight | 82890.71 |
Authors | Singh, A.K.,Blaazer, A.R.,Zara, L.,de Esch, I.J.P.,Leurs, R.,Brown, D.G. (deposition date: 2019-01-12, release date: 2020-02-05, Last modification date: 2024-01-24) |
Primary citation | Singh, A.K.,Brown, D.G. Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-0769 To be published, |
Experimental method | X-RAY DIFFRACTION (1.942 Å) |
Structure validation
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