Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| B | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| B | 0007165 | biological_process | signal transduction |
| B | 0008081 | molecular_function | phosphoric diester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue ZN A 1001 |
| Chain | Residue |
| A | HIS673 |
| A | HIS709 |
| A | ASP710 |
| A | ASP822 |
| A | HOH1104 |
| A | HOH1196 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1002 |
| Chain | Residue |
| A | HOH1167 |
| A | HOH1195 |
| A | HOH1233 |
| A | ASP710 |
| A | HOH1104 |
| A | HOH1110 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue FMT A 1003 |
| Chain | Residue |
| A | GLU768 |
| A | GAI1007 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue FMT A 1004 |
| Chain | Residue |
| A | GLU765 |
| A | ALA767 |
| A | GLU768 |
| A | HOH1225 |
| A | HOH1262 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue FMT A 1005 |
| Chain | Residue |
| A | PHE605 |
| A | ASP606 |
| A | ARG616 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue GAI A 1006 |
| Chain | Residue |
| A | LEU753 |
| A | SER754 |
| A | ASP759 |
| A | ASP762 |
| A | ARG769 |
| A | LEU915 |
| A | HOH1118 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue GAI A 1007 |
| Chain | Residue |
| A | GLU696 |
| A | FMT1003 |
| A | HOH1182 |
| B | TYR686 |
| B | TYR691 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 1008 |
| Chain | Residue |
| A | VAL597 |
| A | LEU598 |
| A | CYS600 |
| A | ARG634 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 1009 |
| Chain | Residue |
| A | VAL610 |
| A | ARG687 |
| A | TRP899 |
| A | HOH1106 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 1010 |
| Chain | Residue |
| A | LEU625 |
| A | ARG660 |
| A | TYR663 |
| A | HOH1231 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue ZN B 1001 |
| Chain | Residue |
| B | HIS673 |
| B | HIS709 |
| B | ASP710 |
| B | ASP822 |
| B | HOH1147 |
| B | HOH1227 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 1002 |
| Chain | Residue |
| B | ASP710 |
| B | HOH1147 |
| B | HOH1160 |
| B | HOH1168 |
| B | HOH1200 |
| B | HOH1214 |
| site_id | AD4 |
| Number of Residues | 1 |
| Details | binding site for residue GAI B 1003 |
| site_id | AD5 |
| Number of Residues | 9 |
| Details | binding site for residue GOL B 1004 |
| Chain | Residue |
| A | TYR691 |
| A | LEU694 |
| A | HOH1240 |
| B | TYR691 |
| B | LEU694 |
| B | GLU696 |
| B | HOH1114 |
| B | HOH1222 |
| B | HOH1234 |
| site_id | AD6 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 1005 |
| Chain | Residue |
| A | TYR686 |
| A | ASN689 |
| A | TYR691 |
| A | HOH1219 |
| B | LYS644 |
| B | GLU696 |
| B | PEG1008 |
| B | HOH1102 |
| site_id | AD7 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 1006 |
| Chain | Residue |
| B | GLY688 |
| B | ASN689 |
| B | GLU692 |
| B | LYS693 |
| B | LEU894 |
| B | GLN895 |
| B | GLY896 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 1007 |
| Chain | Residue |
| B | LEU625 |
| B | ARG660 |
| B | TYR663 |
| B | PHE671 |
| B | HOH1224 |
| site_id | AD9 |
| Number of Residues | 8 |
| Details | binding site for residue PEG B 1008 |
| Chain | Residue |
| A | TYR691 |
| A | HOH1146 |
| B | THR695 |
| B | GLU696 |
| B | LEU697 |
| B | GLU768 |
| B | LEU771 |
| B | GOL1005 |
| site_id | AE1 |
| Number of Residues | 7 |
| Details | binding site for residue J2E B 1009 |
| Chain | Residue |
| B | GLN874 |
| B | PHE880 |
| B | HOH1150 |
| B | HOH1205 |
| B | MET785 |
| B | ASN825 |
| B | GLY873 |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDLdHmGlnNsF |
| Chain | Residue | Details |
| A | HIS709-PHE720 | |
