Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6QGE

Galectin-3C in complex with a pair of enantiomeric ligands: S enantiomer

Summary for 6QGE
Entry DOI10.2210/pdb6qge/pdb
DescriptorGalectin-3, (2~{S},3~{R},4~{S},5~{R},6~{R})-4-[4-(3-fluorophenyl)-1,2,3-triazol-1-yl]-2-[(2~{S})-3-[4-(3-fluorophenyl)-1,2,3-triazol-1-yl]-2-oxidanyl-propyl]sulfanyl-6-(hydroxymethyl)oxane-3,5-diol (3 entities in total)
Functional Keywordscell signalling drug design conformational entropy, sugar binding protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight16261.62
Authors
Manzoni, F.,Verteramo, M.L.,Oksanen, E.,Nilsson, U.J.,Logan, D.T. (deposition date: 2019-01-11, release date: 2019-01-23, Last modification date: 2024-01-24)
Primary citationVerteramo, M.L.,Stenstrom, O.,Ignjatovic, M.M.,Caldararu, O.,Olsson, M.A.,Manzoni, F.,Leffler, H.,Oksanen, E.,Logan, D.T.,Nilsson, U.J.,Ryde, U.,Akke, M.
Interplay between Conformational Entropy and Solvation Entropy in Protein-Ligand Binding.
J. Am. Chem. Soc., 141:2012-2026, 2019
Cited by
PubMed: 30618244
DOI: 10.1021/jacs.8b11099
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.16 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon