6QCK

17beta-hydroxysteroid dehydrogenase 14 variant T205 in complex with FB262

6QCK の概要

• エントリーDOI: 10.2210/pdb6qck/pdb
• 分子名称: 17-beta-hydroxysteroid dehydrogenase 14, DIMETHYL SULFOXIDE, 2-[2-(1,3-benzodioxol-2-yl)ethyl]benzoic acid, ... (7 entities in total)
• 機能のキーワード: fragments, soaking, 17b-hsd14, oxidoreductase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29897.72

構造登録者

Bertoletti, N.,Marchais-Oberwinkler, S.,Heine, A.,Klebe, G. (登録日: 2018-12-28, 公開日: 2020-01-29, 最終更新日: 2024-01-24)

• 主引用文献: Badran, M.J.,Bertoletti, N.,Keils, A.,Heine, A.,Klebe, G.,Marchais-Oberwinkler, S.; Mutational and structural studies uncover crucial amino acids determining activity and stability of 17 beta-HSD14.; J.Steroid Biochem.Mol.Biol., 189:135-144, 2019; PubMed: 30836176; DOI: 10.1016/j.jsbmb.2019.02.009

実験手法

X-RAY DIFFRACTION (1.68 Å)