6Q9W

X-ray structure of compound 15 bound to HdmX: Structural states of Hdm2 and HdmX: X-ray elucidation of adaptations and binding interactions for different chemical compound classes

6Q9W の概要

• エントリーDOI: 10.2210/pdb6q9w/pdb
• 関連するPDBエントリー: 6Q9U
• 分子名称: Protein Mdm4, (4~{S})-4-(4-chlorophenyl)-5-[(1~{S})-1-(3-chlorophenyl)ethyl]-2-(2,4-dimethoxypyrimidin-5-yl)-3-propan-2-yl-4~{H}-pyrrolo[3,4-d]imidazol-6-one, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: apoptosis, hdmx, mdm4
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 24728.26

構造登録者

Kallen, J. (登録日: 2018-12-18, 公開日: 2019-05-15, 最終更新日: 2024-01-24)

• 主引用文献: Kallen, J.,Izaac, A.,Chau, S.,Wirth, E.,Schoepfer, J.,Mah, R.,Schlapbach, A.,Stutz, S.,Vaupel, A.,Guagnano, V.,Masuya, K.,Stachyra, T.M.,Salem, B.,Chene, P.,Gessier, F.,Holzer, P.,Furet, P.; Structural States of Hdm2 and HdmX: X-ray Elucidation of Adaptations and Binding Interactions for Different Chemical Compound Classes.; Chemmedchem, 14:1305-1314, 2019; PubMed: 31066983; DOI: 10.1002/cmdc.201900201

実験手法

X-RAY DIFFRACTION (1.55 Å)