6Q9Q
HDMX (14-111; C17S) COMPLEXED WITH COMPOUND 13 AT 2.1A; Structural states of Hdm2 and HdmX: X-ray elucidation of adaptations and binding interactions for different chemical compound classes
Summary for 6Q9Q
Entry DOI | 10.2210/pdb6q9q/pdb |
Related | 6Q9L |
Descriptor | Protein Mdm4, 6-chloranyl-3-[3-[(1~{S})-1-(4-chlorophenyl)ethyl]-5-phenyl-imidazol-4-yl]-~{N}-[2-(4-cyclohexylpiperazin-1-yl)ethyl]-1~{H}-indole-2-carboxamide, 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, ... (6 entities in total) |
Functional Keywords | hdmx, mdm4, apoptosis |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 49416.73 |
Authors | Kallen, J. (deposition date: 2018-12-18, release date: 2019-05-15, Last modification date: 2024-01-24) |
Primary citation | Kallen, J.,Izaac, A.,Chau, S.,Wirth, E.,Schoepfer, J.,Mah, R.,Schlapbach, A.,Stutz, S.,Vaupel, A.,Guagnano, V.,Masuya, K.,Stachyra, T.M.,Salem, B.,Chene, P.,Gessier, F.,Holzer, P.,Furet, P. Structural States of Hdm2 and HdmX: X-ray Elucidation of Adaptations and Binding Interactions for Different Chemical Compound Classes. Chemmedchem, 14:1305-1314, 2019 Cited by PubMed: 31066983DOI: 10.1002/cmdc.201900201 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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