Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005634 | cellular_component | nucleus |
| A | 0043066 | biological_process | negative regulation of apoptotic process |
| A | 0051726 | biological_process | regulation of cell cycle |
| B | 0005634 | cellular_component | nucleus |
| B | 0043066 | biological_process | negative regulation of apoptotic process |
| B | 0051726 | biological_process | regulation of cell cycle |
| C | 0005634 | cellular_component | nucleus |
| C | 0043066 | biological_process | negative regulation of apoptotic process |
| C | 0051726 | biological_process | regulation of cell cycle |
| D | 0005634 | cellular_component | nucleus |
| D | 0043066 | biological_process | negative regulation of apoptotic process |
| D | 0051726 | biological_process | regulation of cell cycle |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue HUE A 201 |
| Chain | Residue |
| A | MET54 |
| A | HOH317 |
| A | HOH318 |
| B | HIS55 |
| A | GLY58 |
| A | ILE61 |
| A | MET62 |
| A | TYR67 |
| A | GLN72 |
| A | VAL93 |
| A | PRO96 |
| A | LEU99 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue O4B A 202 |
| Chain | Residue |
| A | LYS36 |
| A | LEU81 |
| B | GLN65 |
| B | LEU66 |
| B | TYR76 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 203 |
| Chain | Residue |
| A | ILE37 |
| A | ALA40 |
| A | TYR60 |
| A | LYS64 |
| A | HOH309 |
| A | HOH325 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | binding site for residue HUE B 201 |
| Chain | Residue |
| B | MET54 |
| B | LEU57 |
| B | GLY58 |
| B | ILE61 |
| B | MET62 |
| B | GLN72 |
| B | PHE91 |
| B | VAL93 |
| B | PRO96 |
| B | LEU99 |
| B | HOH301 |
| B | HOH326 |
| C | SER97 |
| C | TYR100 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue O4B B 202 |
| Chain | Residue |
| B | LYS36 |
| D | GLN65 |
| D | LEU66 |
| D | TYR76 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue O4B B 203 |
| Chain | Residue |
| B | HIS39 |
| B | GLY42 |
| B | GLN44 |
| B | HOH320 |
| D | GLU71 |
| D | MET74 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 204 |
| Chain | Residue |
| B | THR49 |
| B | VAL50 |
| B | LYS51 |
| C | ARG104 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 205 |
| Chain | Residue |
| A | HOH312 |
| B | GLY45 |
| B | GLU46 |
| B | MET47 |
| D | ARG88 |
| site_id | AC9 |
| Number of Residues | 11 |
| Details | binding site for residue HUE C 201 |
| Chain | Residue |
| B | LYS94 |
| C | MET54 |
| C | GLY58 |
| C | ILE61 |
| C | TYR67 |
| C | GLN72 |
| C | VAL93 |
| C | PRO96 |
| C | LEU99 |
| C | TYR100 |
| C | HOH315 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue O4B C 202 |
| Chain | Residue |
| A | GLN65 |
| A | LEU66 |
| A | TYR76 |
| C | LYS36 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 C 203 |
| Chain | Residue |
| A | ARG88 |
| C | GLY45 |
| C | GLU46 |
| C | MET47 |
| site_id | AD3 |
| Number of Residues | 12 |
| Details | binding site for residue HUE D 201 |
| Chain | Residue |
| D | ALA41 |
| D | MET54 |
| D | GLY58 |
| D | ILE61 |
| D | MET62 |
| D | TYR67 |
| D | GLN72 |
| D | VAL93 |
| D | PRO96 |
| D | LEU99 |
| D | SO4203 |
| D | HOH310 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue O4B D 202 |
| Chain | Residue |
| C | GLN65 |
| C | LEU66 |
| D | LEU32 |
| D | LYS36 |
| D | LEU81 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 D 203 |
| Chain | Residue |
| D | HIS55 |
| D | TYR56 |
| D | GLN59 |
| D | HUE201 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 D 204 |
| Chain | Residue |
| D | TYR60 |
| D | LYS64 |
| D | LYS36 |
| D | ILE37 |
| D | ALA40 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 D 205 |
| Chain | Residue |
| D | GLY45 |
| D | GLU46 |
| D | MET47 |
| D | HOH303 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 249 |
| Details | Domain: {"description":"SWIB/MDM2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01273","evidenceCode":"ECO:0000255"}]} |
