6Q4Y

Structure of MPT-2, a GDP-Man-dependent mannosyltransferase from Leishmania mexicana, in complex with mannose

Summary for 6Q4Y

Entry DOI	10.2210/pdb6q4y/pdb
Descriptor	LmxM MPT-2, beta-D-mannopyranose, alpha-D-mannopyranose, ... (4 entities in total)
Functional Keywords	transferase
Biological source	Leishmania mexicana MHOM/GT/2001/U1103
Total number of polymer chains	2
Total formula weight	77087.27
Authors	Sobala, L.F.,Males, A.,Bastidas, L.M.,Ward, T.,Sernee, M.F.,Ralton, J.E.,Nero, T.L.,Cobbold, S.,Kloehn, J.,Viera-Lara, M.,Stanton, L.,Hanssen, E.,Parker, M.W.,Williams, S.J.,McConville, M.J.,Davies, G.J. (deposition date: 2018-12-06, release date: 2019-09-18, Last modification date: 2024-01-24)
Primary citation	Sernee, M.F.,Ralton, J.E.,Nero, T.L.,Sobala, L.F.,Kloehn, J.,Vieira-Lara, M.A.,Cobbold, S.A.,Stanton, L.,Pires, D.E.V.,Hanssen, E.,Males, A.,Ward, T.,Bastidas, L.M.,van der Peet, P.L.,Parker, M.W.,Ascher, D.B.,Williams, S.J.,Davies, G.J.,McConville, M.J. A Family of Dual-Activity Glycosyltransferase-Phosphorylases Mediates Mannogen Turnover and Virulence in Leishmania Parasites. Cell Host Microbe, 26:385-399.e9, 2019 Cited by PubMed: 31513773 DOI: 10.1016/j.chom.2019.08.009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation