6Q4Y

Structure of MPT-2, a GDP-Man-dependent mannosyltransferase from Leishmania mexicana, in complex with mannose

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	LmxM MPT-2	polymer	341	38093.2	2	UniProt (E9AND8) Pfam (PF08950)	Leishmania mexicana MHOM/GT/2001/U1103
2	C, E (A, B)	beta-D-mannopyranose	non-polymer		180.2	2	Chemie (BMA)
3	D, F, G (A, B)	alpha-D-mannopyranose	non-polymer		180.2	3	Chemie (MAN)
4	H, I (A, B)	water	water		18.0	306	Chemie (HOH)

Sequence modifications

A, B: 1 - 321 (UniProt: E9AND8)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	76186.5
Non-Polymers*	Number of molecules	5
	Total formula weight	900.8
All*	Total formula weight	77087.3

*Water molecules are not included.