6Q3S
Engineered Human HLA_A2 MHC Class I molecule in complex with TCR and SV9 peptide
Summary for 6Q3S
Entry DOI | 10.2210/pdb6q3s/pdb |
Related | 2BNQ |
Descriptor | HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, SER-LEU-LEU-MET-TRP-ILE-THR-GLN-VAL, ... (8 entities in total) |
Functional Keywords | mhc molecule, engineered disulphide bond, immune system, tcr |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 5 |
Total formula weight | 94622.03 |
Authors | Meijers, R.,Anjanappa, R.,Springer, S.,Garcia-Alai, M. (deposition date: 2018-12-04, release date: 2019-07-24, Last modification date: 2021-02-03) |
Primary citation | Moritz, A.,Anjanappa, R.,Wagner, C.,Bunk, S.,Hofmann, M.,Pszolla, G.,Saikia, A.,Garcia-Alai, M.,Meijers, R.,Rammensee, H.G.,Springer, S.,Maurer, D. High-throughput peptide-MHC complex generation and kinetic screenings of TCRs with peptide-receptive HLA-A*02:01 molecules. Sci Immunol, 4:-, 2019 Cited by PubMed: 31324691DOI: 10.1126/sciimmunol.aav0860 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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