6Q2X
TEAD4 (216-434) COMPLEXED WITH YAP PEPTIDE (60-100) AND MYRISTOATE (COVALENTLY BOUND) AT 2.1A (P41212 CRYSTAL FORM)
Summary for 6Q2X
| Entry DOI | 10.2210/pdb6q2x/pdb |
| Descriptor | Transcriptional enhancer factor TEF-3, Transcriptional coactivator YAP1, GLYCEROL, ... (5 entities in total) |
| Functional Keywords | other, transcription |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 30568.61 |
| Authors | Kallen, J. (deposition date: 2018-12-03, release date: 2019-07-03, Last modification date: 2024-01-24) |
| Primary citation | Furet, P.,Salem, B.,Mesrouze, Y.,Schmelzle, T.,Lewis, I.,Kallen, J.,Chene, P. Structure-based design of potent linear peptide inhibitors of the YAP-TEAD protein-protein interaction derived from the YAP omega-loop sequence. Bioorg.Med.Chem.Lett., 29:2316-2319, 2019 Cited by PubMed: 31235263DOI: 10.1016/j.bmcl.2019.06.022 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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