6Q0A

Crystal structure of MurA from Clostridium difficile, mutation C116D, n the presence of UDP-N-acetylmuramic acid

Summary for 6Q0A

• Entry DOI: 10.2210/pdb6q0a/pdb
• Related: 6q03
• Descriptor: UDP-N-acetylglucosamine 1-carboxyvinyltransferase, 1,2-ETHANEDIOL, (2R)-2-{[(2R,3R,4R,5S,6R)-3-(acetylamino)-2-{[(S)-{[(R)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoic acid, ... (4 entities in total)
• Functional Keywords: antibiotics, peptidoglycan, clostridium difficile, transferase
• Biological source: Peptoclostridium difficile (strain 630)
• Total number of polymer chains: 1
• Total formula weight: 45711.41

Authors

Dopkins, B.J.,Call, C.J.,Thoden, J.B.,Holden, H.M. (deposition date: 2019-08-01, release date: 2019-11-27, Last modification date: 2023-10-11)

• Primary citation: Dopkins, B.J.,Call, C.J.,Thoden, J.B.,Holden, H.M.; Crystal structure of MurA from Clostridium difficile, mutation C116D, n the presence of UDP-N-acetylmuramic acid; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.65 Å)