6Q0A
Crystal structure of MurA from Clostridium difficile, mutation C116D, n the presence of UDP-N-acetylmuramic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | polymer | 421 | 44969.9 | 1 | UniProt (Q18CL1) Pfam (PF00275) | Peptoclostridium difficile (strain 630) | Enoylpyruvate transferase,UDP-N-acetylglucosamine enolpyruvyl transferase,EPT |
| 2 | B (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 3 | C (A) | (2R)-2-{[(2R,3R,4R,5S,6R)-3-(acetylamino)-2-{[(S)-{[(R)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoic acid | non-polymer | 679.4 | 1 | Chemie (EPZ) | |||
| 4 | D (A) | water | water | 18.0 | 277 | Chemie (HOH) |
Sequence modifications
A: 1 - 417 (UniProt: Q18CL1)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| His 0 | - | expression tag |
| Asp 116 | Cys 122 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 44969.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 741.5 | |
| All* | Total formula weight | 45711.4 |
