6PYH
Cryo-EM structure of full-length IGF1R-IGF1 complex. Only the extracellular region of the complex is resolved.
Summary for 6PYH
Entry DOI | 10.2210/pdb6pyh/pdb |
EMDB information | 20524 |
Descriptor | Insulin-like growth factor 1 receptor, Insulin-like growth factor I (2 entities in total) |
Functional Keywords | igf1r, igf1, signaling protein-hormone complex, signaling protein/hormone |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 3 |
Total formula weight | 298223.56 |
Authors | |
Primary citation | Li, J.,Choi, E.,Yu, H.,Bai, X.C. Structural basis of the activation of type 1 insulin-like growth factor receptor. Nat Commun, 10:4567-4567, 2019 Cited by PubMed: 31594955DOI: 10.1038/s41467-019-12564-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.3 Å) |
Structure validation
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