6PJJ
Human PRPF4B bound to benzothiophene inhibitor 224
Summary for 6PJJ
Entry DOI | 10.2210/pdb6pjj/pdb |
Descriptor | Serine/threonine-protein kinase PRP4 homolog, 4-(5-{[(3-aminophenyl)methyl]carbamoyl}thiophen-2-yl)-1-benzothiophene-2-carboxamide, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | serine/threonine-protein kinase prp4 homolog, structural genomics consortium, sgc, transferase, splicing kinase prpf4b, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 166739.80 |
Authors | Godoi, P.H.C.,Santiago, A.S.,Fala, A.M.,Ramos, P.Z.,Sriranganadane, D.,Mascarello, A.,Segretti, N.,Azevedo, H.,Guimaraes, C.R.W.,Arruda, P.,Elkins, J.M.,Counago, R.M.,Structural Genomics Consortium (SGC) (deposition date: 2019-06-28, release date: 2019-08-28, Last modification date: 2023-11-15) |
Primary citation | Godoi, P.H.C.,Santiago, A.S.,Fala, A.M.,Ramos, P.Z.,Sriranganadane, D.,Mascarello, A.,Segretti, N.,Azevedo, H.,Guimaraes, C.R.W.,Arruda, P.,Elkins, J.M.,Counago, R.M. to be published To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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