6PES
Cryo-EM structure of alpha-synuclein H50Q Wide Fibril
Summary for 6PES
Entry DOI | 10.2210/pdb6pes/pdb |
Related | 6PEO |
EMDB information | 20328 20331 |
Descriptor | Alpha-synuclein (1 entity in total) |
Functional Keywords | alpha-synuclein, amyloid, h50q, hereditary mutation, fibril, protein fibril |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 10 |
Total formula weight | 144660.91 |
Authors | Boyer, D.R.,Li, B.,Sawaya, M.R.,Jiang, L.,Eisenberg, D.S. (deposition date: 2019-06-20, release date: 2019-11-27, Last modification date: 2024-03-20) |
Primary citation | Boyer, D.R.,Li, B.,Sun, C.,Fan, W.,Sawaya, M.R.,Jiang, L.,Eisenberg, D.S. Structures of fibrils formed by alpha-synuclein hereditary disease mutant H50Q reveal new polymorphs. Nat.Struct.Mol.Biol., 26:1044-1052, 2019 Cited by PubMed: 31695184DOI: 10.1038/s41594-019-0322-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.6 Å) |
Structure validation
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