6PEG
MIF with a allosteric inhibitor
Summary for 6PEG
Entry DOI | 10.2210/pdb6peg/pdb |
Descriptor | Macrophage migration inhibitory factor, ACETATE ION, GLYCEROL, ... (7 entities in total) |
Functional Keywords | inhibitor, mif, drug discovery, isomerase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 38587.32 |
Authors | Asojo, O.A. (deposition date: 2019-06-20, release date: 2019-11-27, Last modification date: 2023-10-11) |
Primary citation | Cirillo, P.F.,Asojo, O.A.,Khire, U.,Lee, Y.,Mootien, S.,Hegan, P.,Sutherland, A.G.,Peterson-Roth, E.,Ledizet, M.,Koski, R.A.,Anthony, K.G. Inhibition of Macrophage Migration Inhibitory Factor by a Chimera of Two Allosteric Binders. Acs Med.Chem.Lett., 11:1843-1847, 2020 Cited by PubMed: 33062162DOI: 10.1021/acsmedchemlett.9b00351 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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