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6PBF

ZINC9155420-bound TRPV5 in nanodiscs

Summary for 6PBF
Entry DOI10.2210/pdb6pbf/pdb
EMDB information20291 20292
DescriptorTransient receptor potential cation channel subfamily V member 5, (1S)-1-(4-oxo-5-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)ethyl [(2S)-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-2-yl]acetate (2 entities in total)
Functional Keywordstrpv5, trp channel, inhibitor, calcium channel, transport protein
Biological sourceOryctolagus cuniculus (Rabbit)
Total number of polymer chains4
Total formula weight333508.84
Authors
Hughes, T.E.T.,Rosario, J.S.D.,Kapoor, A.,Yazici, A.T.,Fluck, E.C.,Filizola, M.,Rohacs, T.,Moiseenkova-Bell, V.Y. (deposition date: 2019-06-13, release date: 2019-11-06, Last modification date: 2024-03-20)
Primary citationHughes, T.E.,Del Rosario, J.S.,Kapoor, A.,Yazici, A.T.,Yudin, Y.,Fluck, E.C.,Filizola, M.,Rohacs, T.,Moiseenkova-Bell, V.Y.
Structure-based characterization of novel TRPV5 inhibitors.
Elife, 8:-, 2019
Cited by
PubMed: 31647410
DOI: 10.7554/eLife.49572
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (4.2 Å)
Structure validation

217705

건을2024-03-27부터공개중

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