6P5X

Sirohydrochlorin-bound S. typhimurium siroheme synthase

Summary for 6P5X

Entry DOI	10.2210/pdb6p5x/pdb
Descriptor	Siroheme synthase, S-ADENOSYL-L-HOMOCYSTEINE, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	sirohydrochlorin, precorrin-2, tetrapyrrole biosynthesis, cysg, biosynthetic protein
Biological source	Salmonella typhimurium
Total number of polymer chains	2
Total formula weight	102083.56
Authors	Pennington, J.M.,Stroupe, M.E. (deposition date: 2019-05-31, release date: 2020-02-26, Last modification date: 2023-10-11)
Primary citation	Pennington, J.M.,Kemp, M.,McGarry, L.,Chen, Y.,Stroupe, M.E. Siroheme synthase orients substrates for dehydrogenase and chelatase activities in a common active site. Nat Commun, 11:864-864, 2020 Cited by PubMed: 32054833 DOI: 10.1038/s41467-020-14722-1 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.97 Å)

Structure validation