6P1R

Pre-catalytic ternary complex of human DNA Polymerase Mu with 1-nt gapped substrate containing template 8OG and bound incoming AMPNPP

Summary for 6P1R

• Entry DOI: 10.2210/pdb6p1r/pdb
• Descriptor: DNA-directed DNA/RNA polymerase mu, DNA (5'-D(*CP*GP*GP*CP*(8OG)P*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ... (10 entities in total)
• Functional Keywords: family x polymerase, nhej, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 45922.08

Authors

Kaminski, A.M.,Pedersen, L.C.,Bebenek, K.,Chiruvella, K.K.,Ramsden, D.A.,Kunkel, T.A. (deposition date: 2019-05-20, release date: 2019-09-04, Last modification date: 2023-10-11)

• Primary citation: Kaminski, A.M.,Chiruvella, K.K.,Ramsden, D.A.,Kunkel, T.A.,Bebenek, K.,Pedersen, L.C.; Unexpected behavior of DNA polymerase Mu opposite template 8-oxo-7,8-dihydro-2'-guanosine.; Nucleic Acids Res., 47:9410-9422, 2019; PubMed: 31435651; DOI: 10.1093/nar/gkz680

Experimental method

X-RAY DIFFRACTION (1.701 Å)