6P14
Structure of spastin AAA domain (T692A mutant) in complex with a diaminotriazole-based inhibitor (crystal form B)
Summary for 6P14
Entry DOI | 10.2210/pdb6p14/pdb |
Descriptor | Spastin, (4S)-2-METHYL-2,4-PENTANEDIOL, SULFATE ION, ... (6 entities in total) |
Functional Keywords | inhibitor, complex, aaa protein, isomerase-isomerase inhibitor complex, isomerase/isomerase inhibitor |
Biological source | Drosophila melanogaster (Fruit fly) |
Total number of polymer chains | 1 |
Total formula weight | 35066.82 |
Authors | Pisa, R.,Cupido, T.,Kapoor, T.M. (deposition date: 2019-05-17, release date: 2019-07-24, Last modification date: 2023-10-11) |
Primary citation | Pisa, R.,Cupido, T.,Steinman, J.B.,Jones, N.H.,Kapoor, T.M. Analyzing Resistance to Design Selective Chemical Inhibitors for AAA Proteins. Cell Chem Biol, 26:1263-, 2019 Cited by PubMed: 31257183DOI: 10.1016/j.chembiol.2019.06.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.93001125684 Å) |
Structure validation
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