6OXH
X-ray crystal structure of His-tagged Y140F FtmOx1 bound to Fe(II) and 2-oxoglutarate
Summary for 6OXH
Entry DOI | 10.2210/pdb6oxh/pdb |
Descriptor | Verruculogen synthase, FE (II) ION, 2-OXOGLUTARIC ACID, ... (4 entities in total) |
Functional Keywords | endoperoxidation, deprenylation, oxygenase, metalloenzyme, fumitremorgin, verruculogen, oxidoreductase |
Biological source | Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus Af293) |
Total number of polymer chains | 2 |
Total formula weight | 70610.23 |
Authors | Dunham, N.P.,Boal, A.K. (deposition date: 2019-05-13, release date: 2019-07-03, Last modification date: 2023-10-11) |
Primary citation | Dunham, N.P.,Del Rio Pantoja, J.M.,Zhang, B.,Rajakovich, L.J.,Allen, B.D.,Krebs, C.,Boal, A.K.,Bollinger Jr., J.M. Hydrogen Donation but not Abstraction by a Tyrosine (Y68) during Endoperoxide Installation by Verruculogen Synthase (FtmOx1). J.Am.Chem.Soc., 141:9964-9979, 2019 Cited by PubMed: 31117657DOI: 10.1021/jacs.9b03567 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.92 Å) |
Structure validation
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