6OUV

1-deoxy-D-xylulose 5-phosphate synthase (DXPS) from Deinococcus radiodurans with methylacetylphosphonate (MAP) bound

6OUV の概要

• エントリーDOI: 10.2210/pdb6ouv/pdb
• 関連するPDBエントリー: 6OUW
• 分子名称: 1-deoxy-D-xylulose-5-phosphate synthase, 3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-{(1S)-1-HYDROXY-1-[(R)-HYDROXY(METHOXY)PHOSPHORYL]ETHYL}-5-(2-{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: 1-deoxy-d-xylulose 5-phosphate synthase, dxps, thiamine diphosphate, thiamine pyrophosphate, thdp, tpp, changes, the mep pathway, transferase
• 由来する生物種: Deinococcus radiodurans
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 141280.35

構造登録者

Chen, P.Y.-T.,Drennan, C.L. (登録日: 2019-05-05, 公開日: 2019-07-03, 最終更新日: 2023-10-11)

• 主引用文献: Chen, P.Y.,DeColli, A.A.,Freel Meyers, C.L.,Drennan, C.L.; X-ray crystallography-based structural elucidation of enzyme-bound intermediates along the 1-deoxy-d-xylulose 5-phosphate synthase reaction coordinate.; J.Biol.Chem., 294:12405-12414, 2019; PubMed: 31239351; DOI: 10.1074/jbc.RA119.009321

実験手法

X-RAY DIFFRACTION (1.937 Å)