6OU0
Crystal Structure of the D380A/D478S Variant of the Myocilin Olfactomedin Domain
Summary for 6OU0
Entry DOI | 10.2210/pdb6ou0/pdb |
Descriptor | Myocilin, GLYCEROL (3 entities in total) |
Functional Keywords | olfactomedin myocilin beta propeller, protein binding |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 31217.06 |
Authors | Hill, S.E.,Kwon, M.S.,Lieberman, R.L. (deposition date: 2019-05-03, release date: 2019-07-03, Last modification date: 2020-01-15) |
Primary citation | Hill, S.E.,Kwon, M.S.,Martin, M.D.,Suntharalingam, A.,Hazel, A.,Dickey, C.A.,Gumbart, J.C.,Lieberman, R.L. Stable calcium-free myocilin olfactomedin domain variants reveal challenges in differentiating between benign and glaucoma-causing mutations. J.Biol.Chem., 294:12717-12728, 2019 Cited by PubMed: 31270212DOI: 10.1074/jbc.RA119.009419 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.799 Å) |
Structure validation
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