6OPG
phosphorylated ERK2 with AMP-PNP
Summary for 6OPG
| Entry DOI | 10.2210/pdb6opg/pdb |
| Descriptor | Mitogen-activated protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ... (4 entities in total) |
| Functional Keywords | signaling protein, transferase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 41688.84 |
| Authors | Vigers, G.P.,Smith, D. (deposition date: 2019-04-25, release date: 2019-07-31, Last modification date: 2023-11-15) |
| Primary citation | Pegram, L.M.,Liddle, J.C.,Xiao, Y.,Hoh, M.,Rudolph, J.,Iverson, D.B.,Vigers, G.P.,Smith, D.,Zhang, H.,Wang, W.,Moffat, J.G.,Ahn, N.G. Activation loop dynamics are controlled by conformation-selective inhibitors of ERK2. Proc.Natl.Acad.Sci.USA, 116:15463-15468, 2019 Cited by PubMed: 31311868DOI: 10.1073/pnas.1906824116 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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