6OPA

Crystal structure of bovine Fab NC-Cow1 in complex with HIV-1 BG505 SOSIP.664, and human Fabs 35022 and PGT128

6OPA の概要

• エントリーDOI: 10.2210/pdb6opa/pdb
• 分子名称: Envelope glycoprotein gp160, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (15 entities in total)
• 機能のキーワード: hiv-1 broadly neutralizing antibody, viral protein-immune system complex, immune system
• 由来する生物種: Human immunodeficiency virus 1; 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 229340.44

構造登録者

Stanfield, R.L.,Wilson, I.A. (登録日: 2019-04-24, 公開日: 2020-04-01, 最終更新日: 2023-10-11)

• 主引用文献: Stanfield, R.L.,Berndsen, Z.T.,Huang, R.,Sok, D.,Warner, G.,Torres, J.L.,Burton, D.R.,Ward, A.B.,Wilson, I.A.,Smider, V.V.; Structural basis of broad HIV neutralization by a vaccine-induced cow antibody.; Sci Adv, 6:eaba0468-eaba0468, 2020; PubMed: 32518821; DOI: 10.1126/sciadv.aba0468

実験手法

X-RAY DIFFRACTION (4.084 Å)