Splayed open prefusion RSV F captured by CR9501 and motavizumab Fabs

Summary for 6OE5

DescriptorFusion glycoprotein F0,Fibritin, Motavizumab Fab Heavy Chain, Motavizumab Fab Light Chain, ... (5 entities in total)
Functional Keywordsclass i fusion glycoprotein, immunoglobulin, respiratory syncytial virus, trimerization, neutralizing, viral protein, viral protein-immune system complex, viral protein/immune system
Biological sourceHuman respiratory syncytial virus A (strain A2)
Total number of polymer chains5
Total molecular weight156729.87
Gilman, M.S.A.,McLellan, J.S. (deposition date: 2019-03-27, release date: 2019-04-17, Last modification date: 2019-05-22)
Primary citation
Gilman, M.S.A.,Furmanova-Hollenstein, P.,Pascual, G.,B van 't Wout, A.,Langedijk, J.P.M.,McLellan, J.S.
Transient opening of trimeric prefusion RSV F proteins.
Nat Commun, 10:2105-2105, 2019
PubMed: 31068578 (PDB entries with the same primary citation)
DOI: 10.1038/s41467-019-09807-5
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.30570 0.5% 2.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6oe5
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Molmil generated image of 6oe5
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Molmil generated image of 6oe5
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