6OB0

Compound 2 bound structure of WT Lipoprotein Lipase in Complex with GPIHBP1 Mutant N78D N82D produced in HEK293-F cells

6OB0 の概要

• エントリーDOI: 10.2210/pdb6ob0/pdb
• 分子名称: Lipoprotein lipase, Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: lipase, hydrolase-protein binding complex, hydrolase/protein binding
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 267060.35

構造登録者

Arora, R.,Horton, P.A.,Benson, T.E.,Romanowski, M.J. (登録日: 2019-03-19, 公開日: 2019-05-08, 最終更新日: 2023-10-11)

• 主引用文献: Arora, R.,Nimonkar, A.V.,Baird, D.,Wang, C.,Chiu, C.H.,Horton, P.A.,Hanrahan, S.,Cubbon, R.,Weldon, S.,Tschantz, W.R.,Mueller, S.,Brunner, R.,Lehr, P.,Meier, P.,Ottl, J.,Voznesensky, A.,Pandey, P.,Smith, T.M.,Stojanovic, A.,Flyer, A.,Benson, T.E.,Romanowski, M.J.,Trauger, J.W.; Structure of lipoprotein lipase in complex with GPIHBP1.; Proc.Natl.Acad.Sci.USA, 116:10360-10365, 2019; PubMed: 31072929; DOI: 10.1073/pnas.1820171116

実験手法

X-RAY DIFFRACTION (2.81 Å)