6OAU

Apo Structure of WT Lipoprotein Lipase in Complex with GPIHBP1 Mutant N78D N82D produced in GnTI-deficient HEK293-F cells

Summary for 6OAU

Entry DOI	10.2210/pdb6oau/pdb
Descriptor	Lipoprotein lipase, Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	lipase, hydrolase-protein binding complex, hydrolase/protein binding
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	131452.81
Authors	Arora, R.,Horton, P.A.,Benson, T.E.,Romanowski, M.J. (deposition date: 2019-03-18, release date: 2019-05-08, Last modification date: 2023-10-11)
Primary citation	Arora, R.,Nimonkar, A.V.,Baird, D.,Wang, C.,Chiu, C.H.,Horton, P.A.,Hanrahan, S.,Cubbon, R.,Weldon, S.,Tschantz, W.R.,Mueller, S.,Brunner, R.,Lehr, P.,Meier, P.,Ottl, J.,Voznesensky, A.,Pandey, P.,Smith, T.M.,Stojanovic, A.,Flyer, A.,Benson, T.E.,Romanowski, M.J.,Trauger, J.W. Structure of lipoprotein lipase in complex with GPIHBP1. Proc.Natl.Acad.Sci.USA, 116:10360-10365, 2019 Cited by PubMed: 31072929 DOI: 10.1073/pnas.1820171116 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.48 Å)

Structure validation