6O3K

Crystal structure of the unbound Fab fragment of the human HIV-1 neutralizing antibody PGZL1.H4K3

Summary for 6O3K

• Entry DOI: 10.2210/pdb6o3k/pdb
• Related: 6O3D 6O3G 6O3J 6O3L 6O3U 6O41 6O42
• Descriptor: PGZL1.H4K3 light chain, PGZL1.H4K3 heavy chain, GLYCEROL, ... (5 entities in total)
• Functional Keywords: pgzl1.h4k3 anti hiv-1, gp41 mper, membrane lipids, broadly neutralising hiv-1 antibody, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 48425.86

Authors

Irimia, A.,Wilson, I.A. (deposition date: 2019-02-26, release date: 2019-12-04, Last modification date: 2023-10-11)

• Primary citation: Zhang, L.,Irimia, A.,He, L.,Landais, E.,Rantalainen, K.,Leaman, D.P.,Vollbrecht, T.,Stano, A.,Sands, D.I.,Kim, A.S.,Poignard, P.,Burton, D.R.,Murrell, B.,Ward, A.B.,Zhu, J.,Wilson, I.A.,Zwick, M.B.; An MPER antibody neutralizes HIV-1 using germline features shared among donors.; Nat Commun, 10:5389-5389, 2019; PubMed: 31772165; DOI: 10.1038/s41467-019-12973-1

Experimental method

X-RAY DIFFRACTION (1.451 Å)