6O3K

Crystal structure of the unbound Fab fragment of the human HIV-1 neutralizing antibody PGZL1.H4K3

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue GOL L 301

Chain	Residue
L	SER7
L	PRO8
L	GLY9
L	THR10
L	HOH407

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site_id	AC2
Number of Residues	6
Details	binding site for residue GOL L 302

Chain	Residue
L	LYS188
L	HIS189
L	TYR49
L	SER52
L	GLY53
L	ARG54

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site_id	AC3
Number of Residues	5
Details	binding site for residue GOL L 303

Chain	Residue
H	PRO123
L	SER121
L	ASP122
L	GLU123
L	HOH402

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site_id	AC4
Number of Residues	5
Details	binding site for residue GOL L 304

Chain	Residue
L	GLN155
L	ASN158
L	ASP185
L	HIS189
L	HOH413

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site_id	AC5
Number of Residues	5
Details	binding site for residue SO4 L 305

Chain	Residue
L	PRO59
L	GLY60
L	ARG61
L	HOH401
L	HOH531

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site_id	AC6
Number of Residues	11
Details	binding site for residue GOL H 301

Chain	Residue
H	PHE174
H	PRO175
H	SER186
H	LEU187
H	SER188
H	HOH416
L	GLN160
L	SER162
L	SER176
L	SER177
L	THR178

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site_id	AC7
Number of Residues	7
Details	binding site for residue GOL H 302

Chain	Residue
H	GLU97
H	LEU100
H	GLU101
L	ALA55
L	THR56
L	LYS188
L	HOH423

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site_id	AC8
Number of Residues	6
Details	binding site for residue GOL H 303

Chain	Residue
H	GLU150
H	PRO151
H	VAL152
H	PHE174
H	ALA176
H	LEU187

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site_id	AC9
Number of Residues	5
Details	binding site for residue GOL H 304

Chain	Residue
H	GLN105
H	GLY106
H	HOH401
H	HOH411
H	HOH506

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site_id	AD1
Number of Residues	4
Details	binding site for residue SO4 H 305

Chain	Residue
H	SER28
H	PHE29
H	SER30
H	HOH402

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
L	TYR192-HIS198
H	TYR206-HIS212

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