6O3F

Crystal Structure of Lysyl-tRNA Synthetase from Chlamydia trachomatis with complexed with L-lysine and a difluoro cyclohexyl chromone ligand

6O3F の概要

• エントリーDOI: 10.2210/pdb6o3f/pdb
• 関連するPDBエントリー: 6HCU 6HCW
• 分子名称: Lysine--tRNA ligase, ~{N}-[[4,4-bis(fluoranyl)-1-oxidanyl-cyclohexyl]methyl]-6-fluoranyl-4-oxidanylidene-chromene-2-carboxamide, 1,2-ETHANEDIOL, ... (8 entities in total)
• 機能のキーワード: ssgcid, krs, nucleotide binding, aminoacyl trna ligase activity, lysine trna ligase activity, atp binding, lysyl trna aminoacylation, strain uch-1/proctitis, strain d/uw-3/cx, structural genomics, seattle structural genomics center for infectious disease, ligase
• 由来する生物種: Chlamydia trachomatis serovar L2b (strain UCH-1/proctitis)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 125164.83

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2019-02-26, 公開日: 2019-03-27, 最終更新日: 2023-10-11)

• 主引用文献: Dranow, D.M.,Abendroth, J.,Lorimer, D.D.,Horanyi, P.S.,Edwards, T.E.; Crystal Structure of Lysyl-tRNA Synthetase from Chlamydia trachomatis with complexed with L-lysine and a difluoro cyclohexyl chromone ligand; to be published,

実験手法

X-RAY DIFFRACTION (2.4 Å)