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6O02

Monobody (MC3) bound to tyrosine kinase binding domain of E3 ubiquitin ligase CBL

Summary for 6O02
Entry DOI10.2210/pdb6o02/pdb
DescriptorE3 ubiquitin-protein ligase CBL, Monobody (MC3) (2 entities in total)
Functional Keywordsmonobody, sh2 domain, e3 ligase, inhibitor, synthetic binder, protein binding, transferase-protein binding complex, transferase/protein binding
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight46300.01
Authors
Kukenshoner, T.,Pojer, F.,Hantschel, O. (deposition date: 2019-02-15, release date: 2020-08-19, Last modification date: 2024-03-13)
Primary citationKukenshoner, T.,Pojer, F.,Hantschel, O.
Monobody (MC3) bound to tyrosine kinase binding domain of E3 ubiquitin ligase CBL
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.953 Å)
Structure validation

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