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6O02

Monobody (MC3) bound to tyrosine kinase binding domain of E3 ubiquitin ligase CBL

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
E3 ubiquitin-protein ligase CBLpolymer30935790.41UniProt (P22681)
Pfam (PF02262)
Pfam (PF02761)
Pfam (PF02762)
Homo sapiens (Human)Casitas B-lineage lymphoma proto-oncogene,Proto-oncogene c-Cbl,RING finger protein 55,RING-type E3 ubiquitin transferase CBL,Signal transduction protein CBL
2B
(B)
Monobody (MC3)polymer9710509.61synthetic construct
Sequence modifications
A: 47 - 353 (UniProt: P22681)
PDBExternal DatabaseDetails
Gly 45-expression tag
Ser 46-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight46300.0
All*Total formula weight46300.0
*Water molecules are not included.

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PDB entries from 2025-06-11

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