6NXG
Crystal structure of glycylpeptide N-tetradecanoyltransferase from Plasmodium vivax in complex with inhibitor 303a
Summary for 6NXG
Entry DOI | 10.2210/pdb6nxg/pdb |
Descriptor | Glycylpeptide N-tetradecanoyltransferase, MAGNESIUM ION, CHLORIDE ION, ... (9 entities in total) |
Functional Keywords | transferase, structural genomics, seattle structural genomics center for infectious disease, ssgcid, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Plasmodium vivax (strain Salvador I) |
Total number of polymer chains | 3 |
Total formula weight | 146099.08 |
Authors | Staker, B.L.,Mayclin, S.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2019-02-08, release date: 2020-01-01, Last modification date: 2023-10-11) |
Primary citation | Harupa, A.,De Las Heras, L.,Colmenarejo, G.,Lyons-Abbott, S.,Reers, A.,Caballero Hernandez, I.,Chung, C.W.,Charter, D.,Myler, P.J.,Fernandez-Menendez, R.M.,Calderon, F.,Palomo, S.,Rodriguez, B.,Berlanga, M.,Herreros-Aviles, E.,Staker, B.L.,Fernandez Alvaro, E.,Kaushansky, A. Identification of Selective Inhibitors ofPlasmodiumN-Myristoyltransferase by High-Throughput Screening. J.Med.Chem., 63:591-600, 2020 Cited by PubMed: 31850752DOI: 10.1021/acs.jmedchem.9b01343 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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