6NVD

Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with triazole linked compound 9

Summary for 6NVD

• Entry DOI: 10.2210/pdb6nvd/pdb
• Related: 6CVE
• Descriptor: ATP-dependent dethiobiotin synthetase BioD, SULFATE ION, 2',5'-dideoxy-5'-[4-({[(1S,2R)-2-(2-hydroxybenzene-1-carbonyl)cyclopentyl]acetyl}amino)-1H-1,2,3-triazol-1-yl]cytidine, ... (4 entities in total)
• Functional Keywords: enzyme, synthetase, nucleotide triphosphate binding, transferase, ligase
• Biological source: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
• Total number of polymer chains: 4
• Total formula weight: 94242.57

Authors

Thompson, A.P.,Polyak, S.W.,Wegener, K.L.,Bruning, J.B. (deposition date: 2019-02-05, release date: 2020-02-12, Last modification date: 2023-10-11)

• Primary citation: Thompson, A.P.,Polyak, S.W.,Wegener, K.L.,Bruning, J.B.; Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with triazole linked compound 9; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.44 Å)