6NVD
Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with triazole linked compound 9
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | ATP-dependent dethiobiotin synthetase BioD | polymer | 233 | 23285.7 | 4 | UniProt (P9WPQ5) Pfam (PF13500) In PDB | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | DTB synthetase,DTBS,Dethiobiotin synthase |
2 | A, B, C, D | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
3 | D | 2',5'-dideoxy-5'-[4-({[(1S,2R)-2-(2-hydroxybenzene-1-carbonyl)cyclopentyl]acetyl}amino)-1H-1,2,3-triazol-1-yl]cytidine | non-polymer | 523.5 | 1 | Chemie (L4S) | |||
4 | water | water | 18.0 | 381 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 226 (UniProt: P9WPQ5)
PDB | External Database | Details |
---|---|---|
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
Gly 0 | - | expression tag |
Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 93142.7 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 1099.9 | |
All* | Total formula weight | 94242.6 |