6NTP
PTP1B Domain of PTP1B-LOV2 Chimera
Summary for 6NTP
Entry DOI | 10.2210/pdb6ntp/pdb |
Descriptor | Tyrosine-protein phosphatase non-receptor type 1,NPH1-1, MAGNESIUM ION (3 entities in total) |
Functional Keywords | protein tyrosine phosphatase, protein phosphorylation, signaling, diabetes, obesity, cancer, hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 1 |
Total formula weight | 52174.41 |
Authors | Hongdusit, A.,Sankaran, B.,Zwart, P.H.,Fox, J.M. (deposition date: 2019-01-30, release date: 2020-01-22, Last modification date: 2023-10-11) |
Primary citation | Hongdusit, A.,Zwart, P.H.,Sankaran, B.,Fox, J.M. Minimally disruptive optical control of protein tyrosine phosphatase 1B. Nat Commun, 11:788-788, 2020 Cited by PubMed: 32034150DOI: 10.1038/s41467-020-14567-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.89 Å) |
Structure validation
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