6NP0

Cryo-EM structure of 5HT3A receptor in presence of granisetron

6NP0 の概要

• エントリーDOI: 10.2210/pdb6np0/pdb
• EMDBエントリー: 0469
• 分子名称: 5-hydroxytryptamine receptor 3A, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: membrane protein
• 由来する生物種: Mus musculus (Mouse)
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 290284.84

構造登録者

Basak, S.,Chakrapani, S. (登録日: 2019-01-17, 公開日: 2019-07-24, 最終更新日: 2020-07-29)

• 主引用文献: Basak, S.,Gicheru, Y.,Kapoor, A.,Mayer, M.L.,Filizola, M.,Chakrapani, S.; Molecular mechanism of setron-mediated inhibition of full-length 5-HT3Areceptor.; Nat Commun, 10:3225-3225, 2019; PubMed: 31324772; DOI: 10.1038/s41467-019-11142-8

実験手法

ELECTRON MICROSCOPY (2.92 Å)