6NJ9

Active state Dot1L bound to the H2B-Ubiquitinated nucleosome, 2-to-1 complex

6NJ9 の概要

• エントリーDOI: 10.2210/pdb6nj9/pdb
• EMDBエントリー: 9384
• 分子名称: Histone H3.2, Histone H4, Histone H2A type 1, ... (9 entities in total)
• 機能のキーワード: ubiquitin, nucleosome, methyltransferase, structural protein-transferase-dna complex, structural protein/transferase/dna
• 由来する生物種: Xenopus laevis (African clawed frog); 詳細
• タンパク質・核酸の鎖数: 14
• 化学式量合計: 311849.13

構造登録者

Worden, E.J.,Hoffmann, N.A.,Wolberger, C. (登録日: 2019-01-02, 公開日: 2019-02-20, 最終更新日: 2021-06-16)

• 主引用文献: Worden, E.J.,Hoffmann, N.A.,Hicks, C.W.,Wolberger, C.; Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.; Cell, 176:1490-1501.e12, 2019; PubMed: 30765112; DOI: 10.1016/j.cell.2019.02.002

実験手法

ELECTRON MICROSCOPY (2.96 Å)