6NF5

BG505 MD64 N332-GT5 SOSIP trimer in complex with BG18-like precursor HMP1 fragmentantigen binding and base-binding RM20A3 fragment antigen binding

6NF5 の概要

• エントリーDOI: 10.2210/pdb6nf5/pdb
• EMDBエントリー: 7884
• 分子名称: HIV-1 Env BG505 MD64 N332-GT5 SOSIP gp120, 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env BG505 MD64 N332-GT5 SOSIP gp41, ... (10 entities in total)
• 機能のキーワード: hiv-1, hiv envelope, sosip, antibody, trimer, precursor antibody, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Human immunodeficiency virus 1; 詳細
• タンパク質・核酸の鎖数: 18
• 化学式量合計: 394354.09

構造登録者

Ozorowski, G.,Torres, J.L.,Steichen, J.M.,Schief, W.R.,Ward, A.B. (登録日: 2018-12-18, 公開日: 2019-11-06, 最終更新日: 2020-07-29)

• 主引用文献: Steichen, J.M.,Lin, Y.C.,Havenar-Daughton, C.,Pecetta, S.,Ozorowski, G.,Willis, J.R.,Toy, L.,Sok, D.,Liguori, A.,Kratochvil, S.,Torres, J.L.,Kalyuzhniy, O.,Melzi, E.,Kulp, D.W.,Raemisch, S.,Hu, X.,Bernard, S.M.,Georgeson, E.,Phelps, N.,Adachi, Y.,Kubitz, M.,Landais, E.,Umotoy, J.,Robinson, A.,Briney, B.,Wilson, I.A.,Burton, D.R.,Ward, A.B.,Crotty, S.,Batista, F.D.,Schief, W.R.; A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses.; Science, 366:-, 2019; PubMed: 31672916; DOI: 10.1126/science.aax4380

実験手法

ELECTRON MICROSCOPY (3.71 Å)