6NCM
Crystal structure of the human FOXN3 DNA binding domain in complex with a forkhead-like (FHL) DNA sequence
Summary for 6NCM
Entry DOI | 10.2210/pdb6ncm/pdb |
Related | 6NCE |
Descriptor | Forkhead box protein N3, DNA (5'-D(*AP*TP*AP*GP*CP*GP*TP*CP*TP*TP*AP*GP*CP*AP*TP*G)-3'), DNA (5'-D(*TP*CP*AP*TP*GP*CP*TP*AP*AP*GP*AP*CP*GP*CP*TP*A)-3'), ... (5 entities in total) |
Functional Keywords | sequence specific dna binding, regulation of transcription dna templated, dna binding transcription factor activity, forkhead, dna binding protein, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 33199.00 |
Authors | Rogers, J.M.,Jarrett, S.M.,Seegar, T.C.,Waters, C.T.,Hallworth, A.N.,Blacklow, S.C.,Bulyk, M.L. (deposition date: 2018-12-11, release date: 2019-02-27, Last modification date: 2023-10-11) |
Primary citation | Rogers, J.M.,Waters, C.T.,Seegar, T.C.M.,Jarrett, S.M.,Hallworth, A.N.,Blacklow, S.C.,Bulyk, M.L. Bispecific Forkhead Transcription Factor FoxN3 Recognizes Two Distinct Motifs with Different DNA Shapes. Mol. Cell, 74:245-, 2019 Cited by PubMed: 30826165DOI: 10.1016/j.molcel.2019.01.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.704 Å) |
Structure validation
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